Empowering you with science
The science of fertility is complicated and every woman is different. At ivary, we are working hand in hand with the best reproductive endocrinologists, researchers and fertility clinics to support women in their fertility journeys and improve our product.
Dr. Alexander Just
Gynaecologist, expert in female reproductive science, co-founder and medical director at ivary
What is the ovarian reserve?
Your ovarian reserve is the pool of egg cells in your ovaries. It is a finite pool, because the eggs you are born with are the only eggs you have for life. On average, a female is born with 1 to 2 million egg cells, but this number has already decreased to 300,000 – 400,000 by the time of her first period and continues to decrease constantly throughout her fertile lifetime.
Why does this matter? Because without egg cells, you can’t get pregnant. So, understanding your own ovarian reserve helps you understand your current and future fertility lifespan.
The female fertility lifespan
Fertility isn’t an on/off switch – although that would be handy! Instead, over the course of a woman’s life she passes through several reproductive phases, which come with variable and decreasing chances of getting pregnant.
How does fertility develop over time?
The natural course of fertility: Find out what is behind the biological clock and whether time is really ticking when it comes to fertility.
Menopause: farewell to fertility.
Everyone’s fertility is different, which means that not every woman enters menopause at the same age.
In fact, age at menopause can vary anywhere from 40 to 60 years old! Plus, many women can’t get pregnant naturally up to 10 years before menopause begins. Numerous factors influence these ages, such as genetic predispositions, previous pregnancies, and cancer treatments.
Because of all this, testing ovarian reserve is so important and can empower women in their family planning: the Anti-Müllerian Hormone, commonly referred to as AMH, can measure the number of egg cells left in your ovaries and give you a better idea of your fertile lifespan and when you will enter menopause.
What is the Anti-Müllerian Hormone (AMH)?
The Anti-Müllerian Hormone measures the number of egg cells you have left in your ovaries and is the most accurate, available marker for measuring ovarian reserve. It is released by the small, growing egg cells in the ovaries and decreases over time from the age of 25 until menopause.
AMH can be measured using a simple blood test, which can be taken at any day of your cycle. But while measuring AMH is easy, interpreting it is more of a challenge. The best way to interpret AMH is with age-specific AMH percentiles, which help clarify how low or high a woman’s AMH is compared to other women her age. In fact, ivary conducted a study of 1,000 women in order to determine our own age-specific percentiles.
If you like to read then today is your lucky day! We have compiled a list of the most important studies concerning AMH and ovarian reserve, for your perusing pleasure.
Ovarian Aging: Mechanisms and Clinical Consequences
F. J. Broekmans, M. R. Soules, B. C. Fauser
The physiology and clinical utility of anti-Müllerian hormone in women
Dewailly, D., Andersen, C. Y., Balen, A., Broekmans, F., Dilaver, N., Fanchin, R., … Anderson, R. A. (2014).
Ovarian reserve screening: A scientific and ethical analysis
Tremellen, K., & Savulescu, J. (2014)